Increased erosion in the Upper Indus Basin reduces reservoir capacity and jeopardizes the long-term viability of vital facilities like the Tarbela Dam, making sedimentation a significant threat to Pakistan's water and energy security. This study applies the -SWAT model to evaluate the temporal and spatial dynamics of sediment yield in the Upper Indus Basin. The Besham Qila Gauging Station, located upstream of Tarbela Dam, provided streamflow data for the model's calibration and validation. The model was developed using topography, soil, land use/land cover, and meteorological datasets. The model's reliability for watershed-scale evaluation was confirmed by calibration (1994-2008) and validation (2009-2023), demonstrating satisfactory performance statistics. Sub-basins 1, 4, 5, 6, 16, 17, 19, 21, 23, 24, and 25 were identified as major contributors to sediment yield, while Sub-basin 3 was identified as the primary sediment hotspot. Sediment transport was heavily concentrated during the monsoon season (with July as the peak contributing month) and yearly sediment output exhibited significant interannual variability. The Drivers, Pressure, State, Impacts and Response (DPSIR) framework was applied to systematically assess sediment-contributing factors within specific hotspot, subbasin 3, and to develop region-specific management and mitigation strategies. Sub-basin 3 was identified as a critical sediment hotspot characterized by steep slopes, sparse vegetation cover, shallow unstable soils, and glacier melt influence, resulting in rapid runoff and severe erosion. The integrated geospatial and SWAT modeling approach revealed that natural geomorphic processes dominate sediment mobility in the region, significantly increasing downstream sediment loads and threatening the sustainability of the Tarbela Reservoir system. This study provides evidence-based recommendations for priorty sub-basins for sediment monitoring, erosion control, and watershed restoration. The results promote climate-resilient water infrastructure, sustainable hydropower management, and advancement toward SDGs 2, 6, 7, and 13. Pakistan's long-term water-energy resilience can be strengthened and reservoir storage protected bypriortizing sediment hotspot sub-basins for restoration, slipe stabilization, and continuous monitoring.