The incidence, distribution, and clinical, hematological and pathological features of hemoglobinopathies in Pakistan has not been studied well. However, there have been some reports ( Rahimtoola 1960; Saleem, 1974, and Hashmi et al., 1973), both of cases of thalassaemia and abnormal hemoglobinopathies are not infrequent in Pakistan. Programme of population screening for genetic counselling has to be evaluated on a large scale.