A case of sirenomelia is presented which was diagnosed on the basis of postnatal morphological and radiographic findings. The patient had single lower limb and the feet were absent. There was anal atresia and absent external genitalia. Pre-natal ultrasound showed a cyst in the left kidney and high resistive index (RI) of the fetal umbilical artery along with anhydramnios. Recent literature describes and discusses, the ante-natal diagnostic investigations.