The nursing practice environment is a predominant factor that affects nurses' decisions to quit or stay. Aim: to assess the nurses' perception regarding the nursing practice environment and its effect on the intention to quit. Methods: It's a descriptive correlational study design. The samples of the present study include [360] nurses from selected hospitals. Three tools were used; namely, 1) A demographic sheet 2) A practice Environment Scale, and 3) An intention to quit questionnaire. Results: The majority of the nurses perceptions are mixed concerning the practice environment (78.9%). the highest percentage of nurses' perceive a better practice environment in El Rajehy hospital (46.7%), while, the lowest percentage of them is in the main hospital (2.2%). About (67.5%) of the nurses had the intention to quit. Conclusion: There was a negative correlation between the intention to quit and the total practice environment with highly statistically significant differences (P. value <0.01).