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VALPROATE INDUCED HYPERAMMONEMIC ENCEPHALOPATHY

Author(s)
Wajeeha Qayyum Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan
Zaland Ahmed Yousafzai Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan
Muhammad Shahid Iqbal Department of Neurology, Rehman Medical Institute,Peshawar ,Pakistan
Sohail Khan Department of Neurology, Rehman Medical Institute,Peshawar- Pakistan
Qazi Kamran Amin Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan
Ihtesham Shafiq Department of Medicine,Rehman Medical Institute, Peshawar, Pakistan
Abstract
Valproate is a commonly prescribed anticonvulsant drug. It has a potential to cause hyperammonemia even in the presence of normal liver function tests. This hyperammonemic state can lead to encephalopathy referred as Valproate induced hyperammonemic encephalopathy (VHE). Here we present a case of valproate induced hyperammonemic encephalopathy in a young male caused by initiation of valproate therapy.
Publication Details
Page(s) 1038-1039
DOI 10.55519/JAMC-04-S4-10190
Published Journal: Journal of Ayub Medical College, Volume: 34, Issue: 4, Year: 2022

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Keywords
encephalopathy, Valproate, neurology
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