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PROSTATITIS AS AN INITIAL PRESENTATION FOR GRANULOMATOSIS WITH POLYANGIITIS

Author(s)
Nauman Ismat Butt Department of Medicine & Allied, Azra Naheed Medial College Superior University Lahore, Pakistan
Raheel Younus Department of Rheumatology, National hospital and Medical Center Lahore,Pakistan
Muhammad Qasim Khan Tareen Department of Medicine, Sandeman Provinical Hospital, Bolan University of Medical and Health Sciences Quetta ,Pakistan
Sumaira Farman Department of Rheumatology, National hospital and Medical Center Lahore,Pakistan
Nighat Mir Ahmad Department of Rheumatology, National hospital and Medical Center Lahore,Pakistan
Amna Ahmad Department of Rheumatology, National hospital and Medical Center Lahore,Pakistan
Abstract
Granulomatosis with polyangiitis (GPA) is an uncommon pauci-immune small-vessel necrotising granulomatous vasculitis mostly seen in age 45-60 years. We present the case of a formerly healthy 44 years old male presenting with dysuria and intermittent urinary retention for 8 months, not responding to empirical antibiotic therapy and TURP. A prostate biopsy showed necrotising granulomatous prostatitis. Urinalysis demonstrated persistent pyuria and haematuria, but cultures showed no growth. Subsequently he complained of fever, cough, dyspnoea and skin ulcers. CT of the chest showed multiple cavitatory lesions and pleural effusion. On work up, c-ANCA was positive and a diagnosis of granulomatosis with polyangiitis was established. This depicts a rarely seen presentation of prostatitis as the initial feature of GPA.
Publication Details
Page(s) 1043-1045
DOI 10.55519/JAMC-04-S4-10658
Published Journal: Journal of Ayub Medical College, Volume: 34, Issue: 4, Year: 2022

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Keywords
Prostatitis, Granulomatosis with polyangiitis, Vasculitis, c-ANCA
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