Background: To analyze the characteristics of skeletal and extra skeletal Ewing's sarcoma / Primitive Neuroectodermal Tumors PNET . Methods: In this descriptive cross-sectional study cases of skeletal and extra skeletal PNET were analyzed. Age, gender, site of biopsy, and results of Immunohistochemistry were recorded. Results: Out of 80 cases, 65.4 % were males . The age ranged from 1 to 45 years, with the mean age of 18 years. Most frequent age group was the second decade of life(54 %). There were 37 cases of Skeletal Ewing Sarcoma and 43 cases of Extra skeletal PNET. Among the 37 ( 47 % ) cases of Ewing sarcoma of bone, femur (21.62%) was the commonest. Out of the 43 cases of Extra skeletal PNET, 41 had peripheral PNET while 2 had CNS PNET. In the 41 patients of Primitive PNET, head and neck (18.6%) and chest (Askin Tumor) (16.27%) were the commonest. CD 99 was positive in 73 %, while, NSE, and Cytokeratin were positive in 32%. Periodic Acid Schiff was positive in 53 cases. Conclusion: Extra skeletal (53.75%) involvement comprises a larger number of cases as compared to skeletal Ewing's sarcoma. Majority of the cases present in the second decade of life. In skeletal Ewing's Sarcoma, femur is the commonest involved site. Head and neck and chest are the commonest in extraskeletal. In extraskeletal a propensity of the soft tissue around leg is also observed