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Non-celiac Gluten Sensitivity: a Systematic Review.

Author(s)
Maria Tanveer Department of Pharmacy, Quaid-i-Azam University, Islamabad, PakistanPharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan
Ali Ahmed Department of Pharmacy, Quaid-i-Azam University, Islamabad, PakistanPharmacy, Quaid-i-Azam University, Islamabad 45320, Pakistan
Abstract
Non-celiac gluten sensitivity (NCGS) is a wheat associated disorder diagnosed by exclusion diagnosis. This review was conducted to collect current information about NCGS, clinical and pathologic manifestations, and problems faced by health professionals. It also highlights the obstacles faced when adopting a gluten-free diet. A search of international literature was conducted through PubMed and Google Scholar till September 2017. The heterogeneous groups of patients affected by NCGS are composed of a number of subgroups, and each demonstrates different clinical and pathological manifestations. The presence of certain underlying factors can be utilised to identify susceptible individuals, namely, incidence of food allergies in infancy, anti-gliadin IgG-antibodies, activation test for flow cytometric basophils, atopy, and increased intraepithelial duodenal eosinophil presence. There is urgent need for reliable biomarkers to decisively diagnose and differentiate NCGS from related disorders. Patients willing to adopt gluten-free products have to choose from products which have high fat and sugar content.
Publication Details
Page(s) 51-57
DOI DOI not available
Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 29, Issue: 1, Year: 2019

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References
SaponeA,BaiJC,CiacciC,DolinsekJ,GreenPH,HadjivassiliouM, 2012.Spectrum of gluten-related disorders: consensus on new nomenclature and classification,BMC Med 10 13 -
PietzakM., 2012.Celiac disease, wheat allergy, and gluten sensitivity,J Parenter Enter Nutr 36 68S -75S
BiesiekierskiJR,NewnhamED,IrvingPM,BarrettJS,HainesM,DoeckeJD, 2011.Gluten causes gastrointestinal symptoms in subjects without celiac disease: A double-blind randomized placebo-controlled trial,Am J Gastroenterol 106 508 -14
LudvigssonJF,LefflerDA,BaiJC,BiagiF,FasanoA,GreenPHR, 2013.The Oslo definitions for coeliac disease and related terms,Gut 62 43 -52
DiSabatino,A , Corazza,GR, 2012.Nonceliac gluten sensitivity: sense or sensibility?,Ann Intern Med 156 309 -
Czaja-BulsaG, 2015.Non-coeliac gluten sensitivity - A new disease with gluten intolerance,Clin Nutr 189 -94
CarroccioA,MansuetoP,IaconoG,SoresiM,D'AlcamoA,CavataioF, 2012.Non-celiac wheat sensitivity diagnosed by double-blind placebo-controlled challenge: Exploring a new clinical entity,Am J Gastroenterol 107 1898 -906
VoltaU,TovoliF,CicolaR,ParisiC,FabbriA,PiscagliaM, 2012.Serological tests in gluten sensitivity (nonceliac gluten intolerance),J Clin Gastroenterol 46 680 -5
Rubio-TapiaA,KyleRA,KaplanEL,JohnsonDR,PageW,ErdtmannF, 2009.Increased prevalence and mortality in undiagnosed celiac disease,Gastroenterology 137 88 -93
SazziniM,De FantiS,CherubiniA,QuagliarielloA,ProfitiG,MartelliPL, 2016.Ancient pathogen-driven adaptation triggers increased susceptibility to non-celiac wheat sensitivity in present-day European populations,Genes Nutr 11 15 -
LohiS,MustalahtiK,KaukinenK,LaurilaK,CollinP,RissanenH, 2007.Increasing prevalence of coeliac disease over time,Aliment Pharmacol Ther 26 1217 -25
VoltaU,De Giorgio R, 2012.New understanding of gluten sensitivity,Nat Rev Gastroenterol Hepatol 9 295 -9
ElliL,TombaC,BranchiF,RoncoroniL,LombardoV,BardellaM, 2016.Evidence for the presence of non-celiac gluten sensitivity in patients with functional gastrointestinal symptoms: Results from a multicenter randomized double-blind placebo-controlled gluten challenge,Nutrients 8 84 -
EswaranS,GoelA,CheyWD, 2013.What role does wheat play in the symptoms of irritable bowel syndrome?,Gastroenterol Hepatol 9 85 -91
JunkerY,ZeissigS,KimSJ,BarisaniD,WieserH,LefflerDA, 2012.Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4,J Exp Med 209 2395 -408
FraserJS,EngelW,EllisHJ,MoodieSJ,PollockEL,WieserH, 2003.Coeliac disease: in vivo toxicity of the putative immunodominant epitope,Gut 52 1698 -702
MorónB,BethuneMT,CominoI,ManyaniH,FerragudM,LópezMC, 2008.Toward the assessment of food toxicity for celiac patients: Characterization of monoclonal antibodies to a main immunogenic gluten peptide,PLoS One 3 e2294 -
DolfiniE,RoncoroniL,ElliL,FumagalliC,ColomboR,RamponiS, 2005.Cytoskeleton reorganization and ultrastructural damage induced by gliadin in a three-dimensional in vitro model,World J Gastroenterol 11 7597 -601
HowdlePD, 2006.Gliadin, glutenin or both? The search for the Holy Grail in coeliac disease,Eur J Gastroenterol Hepatol 18 703 -6
ClementeMG,De VirgiliisS,KangJS,MacatagneyR,MusuMP,Di PierroMR, 2003.Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function,Gut 52 218 -23
DragoS,El AsmarR,Di PierroM,Grazia ClementeM,SaponeATA,ThakarM, 2006.Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines,Scand J Gastroenterol 41 408 -19
ElliL,DolfiniE,BardellaMT, 2003.Gliadin cytotoxicity and in vitro cell cultures,Toxicol Lett 146 1 -8
LucianiA,VillellaVR,VasaturoA,GiardinoI,PettoelloMantovaniM,GuidoS, 2010.Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPAR downregulation in intestinal epithelial cells and coeliac mucosa,Gut 59 311 -9
MazzarellaG,StefanileR,CamarcaA,GilibertiP,CosentiniE,MaranoC, 2008.Gliadin activates HLA class I-restricted CD8+ T cells in celiac disease intestinal mucosa and induces the enterocyte apoptosis,Gastroenterology 134 1017 -27
AgakidisC,Karagiozoglou-LampoudiT,KalaitsidouM,PapadopoulosT,SavvidouA,DaskalouE, 2011.Enzymelinked immunosorbent assay gliadin assessment in processed food products available for persons with celiac disease: A feasibility study for developing a gluten-free food database,Nutr Clin Pract 26 695 -9
VerduEF,HuangX,NatividadJ,LuJ,BlennerhassettPA,DavidCS, 2008.Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice,Am J Physiol Liver Physiol 294 G217 -25
LavöB,KnutsonL,LööfL,OdlindB,VengeP,HällgrenR, 1989.Challenge with gliadin induces eosinophil and mast cell activation in the jejunum of patients with celiac disease,Am J Med 87 655 -60
TursiA, 2004.Gastrointestinal motility disturbances in celiac disease,J Clin Gastroenterol 38 642 -5
SandersDS,CarterMJ,HurlstoneDP,PearceA,WardAM,McAlindonME, 2001.Association of adult coeliac disease with irritable bowel syndrome: a case-control study in patients fulfilling ROME II criteria referred to secondary care,Lancet 358 1504 -8
SandersD., 2002.Irritable bowel syndrome and coeliac disease,Lancet 359 1436 -7
BeniniL,SembeniniC, 2001.Gastric emptying of realistic meals with and without gluten in patients with coeliac disease. Effect of jejunal mucosal recovery,Scand J Gastroenterol 36 1044 -8
PerriF,PastoreM,ZicolellaA,AnneseV,QuitadamoM,AndriulliA, 2000.Gastric emptying of solids is delayed in celiac disease and normalizes after gluten withdrawal,Acta Paediatr 89 921 -5
SpillerRC,LeeYC,EdgeC,RalphsDN,StewartJS,BloomSR, 1987.Delayed mouth-caecum transit of a lactulose labelled liquid test meal in patients with steatorrhoea caused by partially treated coeliac disease,Gut 28 1275 -82
WahnschaffeU,UllrichR,RieckenEO,SchulzkeJD, 2001.Celiac disease-like abnormalities in a subgroup of patients with irritable bowel syndrome,Gastroenterology 121 1329 -38
CatassiC,FabianiE,IaconoG,D'AgateC,FrancavillaR,BiagiF, 2007.A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease,Am J Clin Nutr 85 160 -6
AkobengAK,ThomasAG, .Systematic review: tolerable amount of gluten for people with coeliac disease,Aliment Pharmacol Ther 27 1044 -52
LesterDR, 2008.Gluten measurement and its relationship to food toxicity for celiac disease patients,Plant Methods 4 26 -
CatassiC,BaiJC,BonazB,BoumaG,CalabròA,CarroccioA, 2013.Non-celiac gluten sensitivity: the new frontier of gluten related disorders,Nutrients 5 3839 -53
WuJHY,NealB,TrevenaH,CrinoM,Stuart-SmithW,Faulkner-HoggK, 2015.Are gluten-free foods healthier than non-gluten-free foods? An evaluation of supermarket products in Australia,Br J Nutr 114 448 -54
BallabioC,UbertiF,Di LorenzoC,BrandoliniA,PenasE,RestaniP, 2011.Biochemical and immunochemical characterization of different varieties of amaranth as a safe ingredient for gluten-free products,J Agric Food Chem 59 12969 -74
BartonSH,KellyDG,MurrayJA, 2007.Nutritional deficiencies in celiac disease,Gastroenterol Clin North Am 36 93 -108
SaturniL,FerrettiG,BacchettiT., 2010.The gluten-free diet: safety and nutritional quality,Nutrients 2 16 -34
BardellaMT,FredellaC,PrampoliniL,MolteniN,GiuntaAM,BianchiPA, 2000.Body composition and dietary intakes in adult celiac disease patients consuming a strict gluten-free diet,Am J Clin Nutr 72 937 -9
ThompsonT, 2000.dietary fiber contents of the gluten-free diet,J Am Diet Assoc 100 1389 -96
AnnibaleB,SeveriC,ChistoliniA,AntonelliG,LahnerE,MarcheggianoA, 2001.Efficacy of gluten-free diet alone on recovery from iron deficiency anemia in adult celiac patients,Am J Gastroenterol 96 132 -7
HallertC,GrantC,GrehnS,GrännöC,HulténS,MidhagenG, 2002.Evidence of poor vitamin status in coeliac patients on a gluten-free diet for 10 years,Aliment Pharmacol Ther 16 1333 -9
CatassiC, 2008.Fasano A. Celiac disease,Curr Opin Gastroenterol 24 687 -91
McGoughN,CummingsJH, 2005.Coeliac disease: A diverse clinical syndrome caused by intolerance of wheat, barley and rye,Proc Nutr Soc 64 434 -50
VivasS,Ruiz de MoralesJG,RiestraS,AriasL,FuentesD,AlvarezN, 2009.Duodenal biopsy may be avoided when high transglutaminase antibody titers are present,World J Gastroenterol 15 4775 -80
ThompsonT, 1999.niacin contents of the gluten-free diet,J Am Diet Assoc 99 858 -62
ClinicaPINI,OlivieriAN,MarcheseL,DesiderioG,PullanoF, 1992., -
SaponeA,LammersKM,CasolaroV,CammarotaM,GiulianoMT,De RosaM, 2011.Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity,BMC Med 9 23 -
BrottveitM,RákiM,BergsengE,FallangLE,SimonsenB,LøvikA, 2011.Assessing possible celiac disease by an HLADQ2-gliadin tetramer test,Am J Gastroenterol 106 1318 -24
BrottveitM,BeitnesACR,TollefsenS,BratlieJE,JahnsenFL,JohansenFE, 2013.Mucosal cytokine response after shortterm gluten challenge in celiac disease and non-celiac gluten sensitivity,Am J Gastroenterol 108 842 -50
ElliottDE, 2014.The pathophysiology of celiac disease,In 4 -51
HalfdanarsonTR,LitzowMR,MurrayJA, 2007.Hematologic manifestations of celiac disease,Blood 109 412 -21
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