Because of high risk and instability of the patients in Intensive care unit (ICU), the design of ICU is very difficult. ICU design, auxiliary building design, lighting design, noise control and other aspects can also enhance its management. In this paper, we compare ICU design in China and Holland based on related standards. We also premeditate the indoor environment from planning perspective; analyze patients, their families, medical staff and space requirement to conduct research in ICU design. With the social progress and science development, we more and more emphasize human-center design. All of our goal is to provide comfortable and effective ICU environment for patients, their families and medical staff, satisfying the demands of different needs and balancing the economy, quality and efficiency.