JanAT,LeeEJ,ChoiI., 2016.Fibromodulin: a regulatory molecule maintaining cellular architecture for normal cell function,Int J Biochem Cell Biol 80 66 -70
LozzuRV,SchaeferL, 2010.Signaling mechanism evoked by the small Leucine-rich proteoglycans,FEBSJ 227 3864 -75
MormoneE,LuY,GeX,FielMI,NietoN.,Fibromodulin, 2012.an oxidative stress-sensitive proteoglycan, regulates the fibrogenic response to liver injury in mice,Gastroenterology 142 612 -21
ShaniA,GustafssonR, 2013.Fibromodulin deficiency reduces low density lipoprotein accumulation in atherosclerotic plaques in apolipoprotein E-null mice,Arterioscler Thromb Vasc Biol 33 354 -61
SztrolovicsR,ChenXN,GroverJ,RoughleyPJ,KorenbergJR, 1994.Localization of human fibromodulin gene (FMOD) to chromosome 1q32 and completion of C DNA sequence,Genomics 23 715 -7
BellaJ,HindleKL,Mc EwanPA,LovellSC, 2008.The leucine-rich repeat structure,Cell Mol Life Sci 65 -2307
ParacuellosP,KalamajskiS,BonnaA,DominiqueB,FarndaleRW, 2017.Structural and functional analysis of two small leucine-rich proteoglycans, fibromodulin and chondroadherin,Matrix Biol 63 106 -16
McEwanPA,ScottPG,BishopPN,BellaJ, 2006.Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans,J Struct Biol 155 294 -305
KalamajskiS,OldbergA, 2007.Fibromodulin binds collagen type I via Glu 353 and Lys 355 in leucine-rich repeat 11,J Biol Chem 282 26740 -5
KalamajskiS,BihanD,BonnaA,RubinK,FarndaleRW, 2016.Fibromodulin interacts with collagen cross-linking sites and activates lysyloxidase,J Biol Chem 291 7951 -60
HaglandL,TillgrenV,AddisL,WenglonC,ReckliesA,HeiregardD, 2011.Identification and characterization of the integrin 21 binding motifin chondroadherin mediating cell attachment,J Biol Chem 286 3925 -34
TillgrenV,MorgelinM,OnnerfjordP,KalamajskiS,AspbergA, 2016.The tyrosine sulfate domain of fibromodulin binds collagen and enhances fibril formation,J Biol Chem 291 23744 -55
EzuraY,ChakravartiS,OldbergA,ChervonevaI,BirkDE, 2000.Differential expression of lumican and fibromodulin regulate collagen fibrillogenesis in developing mouse tendons,J Cell Biol 151 779 -88
ChakravartiS., 2003.Functions of Lumican and fibromodulin: lessons from knock-out mice,Glycoconj J 19 287 -93
LeeEJ,JanAT,BaigMH, 2016.Fibromodulin: master regulator of myostatin controlling progression of satellite cells through myogenic program,FASEB J 301 2708 -19
TillgrenV,OnnerfjordP,HaglundL,HeinegardD., 2009.Tyrosine sulfate-rich domains of the LRR proteins fibromodulin and osteadherin binds motifs of basic clusters ina variety of heparin-binding proteins; including bioactive factors,J Biol Chem 284 22543 -53
LiCS,YangP,TingK., 2016.Fibromodulin reprogrammed cells: a novel cell source for bone regeneration,Biomaterials 83 194 -206
ZhengZ,JianJ,ZhangX, 2012.Reprogramming of human fibroblasts into multipotent cells with a single ECM proteoglycan, fibromodulin,Biomaterials 33 5821 -31
JianJ,ZhengZ,ZhangK., 2013.Fibromodulin promoted in vitro and in vivo angiogenesis,Biophys Res Commun 436 530 -5
LianN,LiT, 2016.Growth factor pathways in hypertrophic scars: Molecular pathogenesis and therapeutic implications,Biomed Pharmacother 84 42 -50
PhanishMW,WahabNA,Colville-NashP,HendryBM,DockrellME, 2006.The differential role of Smad 2 and Smad 3 in the regulation of pro-fibrotic TGF beta 1 responses in human proximal-tubule epithelial cells,Biochem J 393 601 -7
KobayashiT,LiuX,WenFQ, 2005.Smad 3 mediates TGF Beta 1 induction of VEGF production in lung fibroblasts,Biochem Biophys Res Commun 327 393 -8
LiboiE,Di FrancescoP,GallinariP., 1988.TGF beta induces a sustained C-fos expression associated with stimulation or inhibitor of cell growth in EL2 or NIH 3T3 fibroblasts,Biochem Biophys Res Commun 151 298 -305
KimSJ,AngelP,LafyatisR, 1990.Auto-immune of transforming growth factor B1 is mediated by the AP-1 complex,Mol Cell Biol 10 1492 -7
Ten-DjjkeP,ArthurHM, 2007.Extracellular control of TGF beta signaling in vascular development and disease,Nat Rev Mol Cell Biol 8 857 -69
JunJ II,LauLF, 2011.Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets,Nat Rev. Drug Discov 10 945 -63
ChenCC,ChenN,LauLF, 2001.The angiogenic factors Cyr 61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts,J Biol Chem 276 10443 -52
ZhengZ,JamesAW,LiC, 2017.Fibromodulin reduces scar formation in adult cutaneous wounds by eliciting a fetal-like phenotype,Signal Transduction Targeted Ther 2 e17050 -
ZhengZ,ZhangX,DengC, 2016.Fibromodulin is essential for fetaltype scarless cutaneous wound healing,Am J Pathol 186 2824 -32
SooC,HuFY,ZhangY., 2000.Differential expression of fibromodulin, a transforming growth factor beta modulator, in fetal skin development and scarless repair,Am J Pathol 157 423 -33
WalravenM,AkershoeJJ,BeelenRH,UlrichMM, 2017.In vitro cultured fetal fibroblasts have myofibroblast associated upon stimulation with TGF - B1: Is there a thin line between fetal scarless healing and fibrosis?,Arch Dermatol Res 309 111 -21
ColwellAS,BeavesSR,SooC, 2005.Increased angiogenesis and expression of vascular endothelial growth factor during scarless repair,Plast Reconstr Surg 115 204 -12
LiuPP,ChanLS,LeeYW,FuSC,ChanKM, 2010.Sustained expression of proteoglycans and collagen type III / type I ratio in a calcified tendinopathy model,Rheumatology 49 231 -9
SamiricT,ParkinsonJ,LlicMZ, 2009.Changes in the composition of the extracellular matrix in patellar tendinopathy,Matrix Biol 28 230 -6
DelalandeA,GosselinMP,SuwalskiA, 2015.Enhanced Achilles tendon healing by fibromodulin gene transfer,Nanomedicine 11 1735 -44
RoughleyPJ,WhiteRJ,Cs-SzaboG,MortRS, 1996.Changes with age in the structure of fibromodulin in human articular cartilage,Osteoarthritis Cartilage 4 153 -61
Cs-SzaboG,RoughleyPJ,PlaasAH,GlantTT, 1995.Large and small proteoglycans of osteoarthritis and rheumatoid articular cartilage,Arthritis Rheum 38 660 -8
EmbreeMC,KiltsTM,OnoN., 2010.Biglycan and fibromodulin have essential roles in regulating chondrogenesis and extracellular matrix turnover in temporomandibular joint osteoarthritis,Am J Pathol 176 812 -26
WadhwaS,EmbreeM,AmeyeL,YoungMF, 2005.Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis,Cells Tissues Organs 181 136 -43
OkamotoK,KigaN,ShirohanY,TojyoI,FujitaS, 2015.Effect of interleukin-1 beta and dehydroepiandrosterone on the expression of lumican and fibromodulin in fibroblast-like synovial cells of the human temporomandibular joint,Eur J Histochem 59 2440 -
JepsenKJ,WuF,PeragalloJH, 2002.A syndrome of joint laxity and impaired tendon integrity in lumican and fibromodulin deficient mice,J Biol Chem 227 35532 -40
BrownS,MelroseJ,CatersonB., 2012.A comparative evaluation of the small leucine -rich proteoglycans of pathological human intervertebral discs,Eur Spine J 21 145 -9
MelroseJ,SmithSM,FullerES, 2007.Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodeling in experimentally injured ovine intervertebral discs,Eur Spine J 16 2193 -205
SztrolovicsR,AliniM,MortJS,RoughleyPJ, 1999.Age-related changes in fibromodulin and lumican in human intervertebral discs,Spine (Phila Pa 24 1765 -71
ShamiA,TengrydC, 2015.Expression of fibromodulin in carotid atherosclerotic plaques is associated with diabetes and cerebrovascular events,Atherosclerosis 241 701 -8
RanjzadP,SalemHK,KinstonPA, 2009.Adenovirus-mediate gene transfer of fibromodulin inhibits neointimal hyperplasia in an organ culture model of human saphenous vein graft disease,Gene Ther 16 1154 -62
GoldbergM,SeptierD,OldbergA,YoungMF,AmeyeLG, 2006.Fibromodulin-deficient mice display impaired collagen fibrillogenesis in predentin as well as altered dentin mineralization and enamel formation,J Histochem Cytochem 54 525 -37
GoldbergM,OnoM,SeptierD, 2009.Fibromodulin-deficient mice reveal dual functions for fibromodulin in regulating dental tissue and alveolar bone formation,Cells Tissues Organs 189 198 -202
StankoskaK,SarramL,Smith S, 2016.Immuno-localization and distribution of proteoglycans in carious dentine,Aust Dent J 61 288 -97
AlimohamadH,HabijanacT,LarjavaH, ., -
2005.Colocalization of the collagen-binding proteoglycans decorin, biglycan, fibromodulin, and lumican with different cells in human gingiva,J Periodontal Res 40 73 -86
QianH,XiaoY,BartoldPM, 2004.Immuno-histochemical localization and expression of fibromodulin in adult rat periodontium and inflamed human gingiva,Oral Dis 10 233 -9
WangL,FosterBL,KrumV, 2014.Fibromodulin and biglycan modulate periodontium through TGF / BMP signaling,J Dent Res 93 780 -7
LucarielloA,TrabuccoE,BocciaO, 2015.Small leucine rich proteoglycans are differently distributed in normal and pathologicalendometrium,In Vivo 29 217 -22
LeversS,LuoX,DingL,WilliamsRS,CheginiN., 2005.Fibromodulin is expressed in leiomyoma and myometrium and regulated by gonadotropin-releasing hormone analogue therapy and TGFbeta through Smad and MAPK-mediated signaling,Mol Hum Reprod 11 489 -94
HalderSK,OsteenKG,Al-HendyA, 2013.-dihydroxyvitamin d3 reduced extracellular matrix-associated protein expression in human uterine fibroid cells,Biol Reprod 89 150 -
Olof-OlssonP,KalamajskiS,MaccaranaM,OldbergA,RubinK., 2017.Fibromodulin deficiency reduces collagen structural network but not glycosaminoglycan content in a syngeneic model of colon carcinoma,Plos One 12 e0182973 -
OldbergA,KalamajskiS,SalnikovAV, 2007.Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma,Proc Natl Acad Sci USA 104 13966 -71
Dawoody-NejadL,BiglariA,AnneseT,RibattiD., 2017.Recombinant fibromodulin and decorin effects on NF-KB and TGFB1 in the 4T1 breast cancer cell line,Oncol Lett 13 4475 -80
ReyesN,BenedettiI,BettinA,RebolloJ,GeliebterJ, 2016.The small leucine rich proteoglycan fibromodulin is overexpressed in human prostate epithelial cancer cell line in culture and human prostate cancer tissue,Cancer Biomark 16 191 -202
BettinA,ReyesI,ReyesN., 2016.Gene expression profiling of prostate cancer-associated genes identifies fibromodulin as potential novel biomarker for prostate cancer,Int J Biol Markers 31 e153 -162
MondalB,PatilV,ShwethaSD, 2017.Integrative functional genomic analysis identifies epigenetically regulated fibromodulin as an essential gene for glioma cell migration,Oncogene 36 71 -83
AoZ,YuS,QianP, 2017.Tumor angiogenesis of SCLC inhibited by decreased expression of FMOD via down-regulating angiogenic factors of endothelial cells,Biomed Pharmacother 87 539 -47
AdiniI,GhoshK,AdiniA, 2014.Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment,J Clin Invest 124 425 -36
MayrC,BundD,SchleeM, 2005.Fibromodulin as a novel tumor associated antigen (TAA) in chronic lymphocytic leukemia (CLL), which allows expansion of specific CD8 + autologous T-lymphocytes,Blood 105 1566 -73
Rydell-TormonenK,AndreassonK,HesselstrandR,Westergren-ThorssonG, 2014.Absence of fibromodulin affects matrix composition, collagen deposition and cell turnover in healthy and fibrotic lung parenchyma,Sci Rep 4 6383 -
KramV,KiltsTM,BhattacharyyaN,LiL,YoungMF, 2017.Small leucine rich proteoglycans, a novel link to osteoclastogenesis,Sci Rep 7 12627 -
JaziMF,BiglariA,MazloomzadehS., 2016.Recombinant fibromodulin has therapeutic effects on diabetic nephropathy by downregulating transforming growth factor - B1 in streptozotocininduced diabetic rat model,Iran J Basic Med Sci 19 265 -71
HeppnerJM,ZanckeF,ClarkeLA, 2015.Extracellular matrix disruption is an early event in the pathogenesis of skeletal disease in mucopolysaccharidosis I,Mol Genet Metab 114 146 -55