Software is an important component of Large Information Weapon (LIW). We propose a data-driven distributed automatic testing framework, which is based on the analysis of LIW testing requirements, and it supports the whole process of distributed software test. The main components of the framework consist of distributed test designing environment, execution and control environment and test results show environment. We present a set of GUI scripting language specification for automatic testing, the script language with object-oriented features. Unlike the previous GUI automatic testing scripting language, this specification records the information of the node where the test cases will be running. As an application of the framework, we develop an automatic testing system (DMATS). DMATS has been put into practices in XXX-business electronic system, and it is proved the feasibility of the framework.