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Persistent status epilepticus due to bupropion intoxication.

Author(s)
Cevdet Duger Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Ahmet Cemil Isbir Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Kenan Kaygusuz Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Iclal Ozdemir Kol Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Sinan Gursoy Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Caner Mimaroglu Department of Anesthesiology and Reanimation Cumhuriyet University, School of Medicine, 58140 Sivas, Turkey
Abstract
Bupropion is a generally well-tolerated drug and has adverse effects such as headache, dizziness, dry mouth, nausea, constipation, tremor, drowsiness, agitation, insomnia, hallucinations, allergic reactions and seizures. Although seizures have been reported with therapeutic doses of bupropion, there are few reports presenting development of status epilepticus due to bupropion intoxication with different doses. This rare case of persistent status epilepticus due to intoxication with 9 gm bupropion describes a surviving patient after one of the highest ingested dose cited in literature. We indicate that early management is crucial for patients with intoxication with massive doses of bupropion.
Publication Details
Page(s) 302-304
DOI DOI not available
Published Journal: Anaesthesia, Pain and Intensive Care, Volume: 16, Issue: 3, Year: 2012

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