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Effect of Botulinum Toxin a & Task-specific Training on Upper Limb Function in Post-stroke Focal Dystonia.

Author(s)
Muhammad Umar Holy Family Hospital, Islamabad
Tahir Masood Isra Institute of Rehabilitation Sciences, Isra University, Islamabad Campus, Islamabad
Mazhar Badshah Pakistan Institute of Medical Sciences, Islamabad.
Abstract
Objective: To determine the effect of botulinum toxin A and task-specific training on upper limb function in poststroke focal dystonia patients. Methods: A randomised control trial was conducted at hospitals in Rawalpindi and Islamabad, Pakistan, from October 2015 to September 2016. The subjects were recruited using non-probability purposive sampling and were divided equally into control and experimental groups by sealed envelope method. The experimental group received botulinum toxin A followed by task-specific training, while the control group received only task-specific training for 8 weeks. Data was collected at baseline, after 4 weeks and 8 weeks by using upper extremity items of Motor Assessment Scale and Fugl-Meyer Assessment scale of upper limb. Results: There were 43 subjects divided into two equal groups of 23(50%) each. In the experimental group, mean age of patients was 43.57±10.94 years while in the control group it was 48.75±10.75 years (p=0.135). There were 15(71.4%) male and 6(28.6%) female patients in the experimental group and 9(45%) were male and 11(55%) were female in the control group. Both groups showed significant improvements on the Motor Assessment Scale and Fugl-Meyer Assessment scale (p0.05). Conclusion: Eight weeks of task-specific training improved upper limb function in post-stroke focal dystonia patients.
Publication Details
Page(s) 526-531
DOI DOI not available
Published Journal: Journal of Pakistan Medical Association, Volume: 68, Issue: 4, Year: 2018

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