Research studies conducted during the past 3 decades have witnessed sig-nificant advancement of food irradiation processing in Pakistan and other countries. Technological and economic feasibility as well as wholesomeness of irradiated food upto 10 kGy had been clearly established. Application of this technology for reducing postharvest food losses, improving hygienic quality, quarantine treatment and insect disinfestations instead of fumigation has been evaluated in detail. At present, 37 countries have approved one or more food items for human consumption and 25 countries have commercialized this process. Decontamination of animal feed for microorganisms especially pathogens by gamma irradiation has been experimentally tested in Pakistan and is commercially carried out in other countries. Pakistan has established a commercial irradiator PARAS in Lahore for sterilizing medical supplies, and the efforts to establish lagislation (regulations) for food irradiation are continuing. In order to facilitate and regulate inter-country trade for irradiated food materials, a programme under the aegis of LAEA for development of detection methods and lable dosimeters to identify irradiated food is in progress in Pakistan and elsewhere.