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Reverse phase high performance liquid chromatographic method for the determination of paracetamol in human serum.

Author(s)
Nadeem Iqbal Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan
Bashir Ahmad Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan
Khalid Hussain Janbaz Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan
Abdul Subhan Ijaz Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan
Nazar Muhammad Ranjha Pharmacy Department, Bahauddin Zakariya University (BZU), Multan, Pakistan
Abstract
A simple, rapid and sensitive high performance liquid chromatographic method was developed for the quantification of paracetamol in human serum. The analysis procedure involved an extraction of paracetamol from the human serum with acetonitrile, using reverse phase column. with a mobile phase acetonitrile and water (25. 75 v/v) at 254 nm, gave an adequate separation and efficient resolution of the required drug.
Publication Details
Page(s) 221-222
DOI DOI not available
Published Journal: Science International, Volume: 3, Issue: 3, Year: 1991

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