Pathogen-derived resistance strategies using coat proteins, movement proteins, non-structural proteins, replicases, antisense and satellite RNAs for the production of virus-resistant transgenic plants are briefly discussed. The concept of recombination of viral RNA with transgene products is critically analyzed and potential risks associated with commercialization of transgenic plants with viral RNA with transgene products is critically analyzed and potential risks associated with commercialization of transgenic plants with viral inserts and its effects on bio-safety, are highlighted.32.51 Weeds