Studies on some &alpha;-&beta; -unsaturated nitriles.

M. M. Mohamed; M. A. El-Hashash; A. El Naggar; F. Said; W. M. Ali

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Studies on some α-β -unsaturated nitriles.

Author(s)

M. M. Mohamed Chemistry Department, Faculty of Education, Ain Shams University, Cairo, Egypt

M. A. El-Hashash Chemistry Department, Faculty of Education, Ain Shams University, Cairo, Egypt

A. El Naggar Chemistry Department, Faculty of Education, Ain Shams University, Cairo, Egypt

F. Said Chemistry Department, Faculty of Education, Ain Shams University, Cairo, Egypt

W. M. Ali Chemistry Department, Faculty of Education, Ain Shams University, Cairo, Egypt

Abstract

Previously we had reported the behaviour of some α,β-unsaturated arylidene malononitriles and other related compounds toward the action of active methylene compounds and other reactions. In this study investigations are extended to arylidene malononitriles (I) for the purpose of their biological evaluation. The arylidene malononitriles (I) react with active methylene compounds, Grignard reagents, diazomethane and hydrazine hydrate and give compounds (II-XIII). The antimicrobial and antifungal activities of the prepared organic compounds were determined.

Publication Details

Page(s) 169-176

DOI DOI not available

Published Journal: Pakistan Journal of Scientific and Industrial Research, Volume: 23, Issue: 5, Year: 1980

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