Various drugs including histamine, ranitidine, pirenzepine and neuroleptic agents used in gastro-enterology have been described. Treatment with drugs and surgery for duodenal ulcer, colon, liver, transhepatic cholangiography, hepatic transplantation, gall- bladder, endoscopic sphincterotomy and gall stone removal, radionuclide evaluation of gall bladder and ultrasonography have been dealt.