Total demographic/population potential created at a point in a certain region is the summation of separate potentials induced by all other points PLUS self potential of that point. This paper applies the concept to the province of Sind. The analysis reveals that the central strip running along the Indus enjoys higher potential and throws up two pronounced peaks at Hyderabad and Sukkur; a nascent upcoming outcrop is discerned near Moro. Karachi emerges as the second highest peak after Hyderabad. In addition, a high plateau between Hyderabad and Karachi along super highway shows up as a powerful development axis which threatens to pre-empt the development possibilities in the rest of the Province. The situation calls for countering the existing trends through setting up of growth centres in the periphery so as to achieve balanced development of the province.