Aganglionic disease of the colon is commonly known as Hirschsprung`s disease, after the name of Professor Hirschsprung of Copenhagen who first estab-lished its separate identity and presented two cases with signs and symptoms as well as with postmortem findings in 1887. He thought the dilated part of the colon was the diseased area. In 1948, Swenson, Wilson and Bodian established the aetiology by showing the absence of the para-sympathetic ganglia in the diseased part of the colon. This paper describes the author`s experience with 37 cases of Hirschsprung`s disease, recorded from 1971-1978. A majority of these cases belonged to the neonatal category. Only two were adults.