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Sarcoidosis.

Author(s)
R. M. Sadiq North Logan Avenue, Danville, Monis, USA
Abstract
Sarcoidosis is a multisystem disease which has been recognized for slightly more than a century. At the Seventh International Congress on sarcoidosis and other granulomatous disorders, New York, 1975, the international committee described the disorder as a multisystem, granulomatous disorder of unknown etiology, most commonly affecting young adults and presenting most frequently with bilateral hilar lymphadenopathy, pulmonary infiltration, skin or eye lesions. The diagnosis is established most securely when clinico-radiographic findings are supported by histological evidence of widespread non-caseating epitheliod cell granulomas in more than one organ or a positive Kveim-Ziltzbach skin test. Immunological features are depression or delayed-type hypersensitivity, suggesting impaired cell mediated immunity and raised or abnormal immunoglobulins. There may also be hypercalcemia. The lung and thoracic lymph nodes, liver, skin and eyes are most commonly involved. The heart, gastrointestinal tract, kidneys and brain way also be involved. Cortidsteroids relieve symptoms and suppress inflammation and granule-formation.
Publication Details
Page(s) 3-9
DOI DOI not available
Published Journal: Challenge, Volume: 20, Issue: 1--4, Year: 1979

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