Case of a seventy years old Libyan is described who was suffering from cough and progressive shortness of breath. He was found to have `Honey Comb" Lungs and classical triad of Schuller Christian Disease, that is multiple skeletal lesions, exophthalmos and diabetes insipidus. Transaminases which have not been mentioned abnormal in this disease were reported to be raised on various occasions in the patient which may be due to his involvement of liver and other viscera.