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Central sensitization: Neurons are awake; are we?

Author(s)
Preetveen Kaur Department of Anesthesiology, Sri Guru Ram Das Institute of Medical Sciences & Research (SGRDIMSR), Mehta Road, Vallah, Amritsar, Punjab, India
Ruchi Gupta Department of Anesthesiology, Sri Guru Ram Das Institute of Medical Sciences & Research (SGRDIMSR), Mehta Road, Vallah, Amritsar, Punjab, India
Saru Singh Department of Anesthesiology, Bhagat Phool Singh Govt. Medical College (BPS GMC), Khanpur Kalan, Sone-pat, India
Mallika Mahindru Department of Anesthesiology, Sri Guru Ram Das Institute of Medical Sciences & Research (SGRDIMSR), Mehta Road, Vallah, Amritsar, Punjab, India
Jagdeep Sharma Department of Anesthesiology, Sri Guru Ram Das Institute of Medical Sciences & Research (SGRDIMSR), Mehta Road, Vallah, Amritsar, Punjab, India
Abstract
Central sensitization (CS) is a known entity associated with prolonged intense painful stimulation secondary to neuropathic or inflammatory peripheral disease and manifests as a heightened responsiveness of the patient to even mild peripheral input. Although numerous protocols are available for its treatment, there have been no reports about the patient`s behavior under anesthesia while operating for related or non-related surgery and management thereof. These patients might require high doses of anesthetic agents to achieve the required depth of anesthesia for surgery. We present three reports of patients who required high doses of anesthetic agents for optimum operative conditions. Two of these were managed with ketamine.
Publication Details
Page(s) 394-398
DOI DOI not available
Published Journal: Anaesthesia, Pain and Intensive Care, Volume: 19, Issue: 3, Year: 2015

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