No Detail Found!

Unique side effects of interferon.

Author(s)
Hina Aslam Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Rashid Qadeer Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Syed Mohammad Kashif Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Muhammad Rehan Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Salahuddin Afsar Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan
Abstract
Interferon-alpha, a potent mediator of host immune response, has immunomodulatory properties in addition to its antiviral effects. A wide spectrum of autoimmune diseases can occur in patients treated with interferonalpha for chronic hepatitis B and D, of which clinical systemic lupus erythematosus (SLE) accounts for less than 1% and hypothyroidismfor 2-4 %.We report herein a case of a 16-year-old male who developed antinuclear antibody (ANA)-negative SLE and hypothyroidism after treatment with interferon-alpha for chronic hepatitis. High index of suspicion is therefore necessary in all patients treated with interferon for early diagnosis and treatment.
Publication Details
Page(s) 895-897
DOI DOI not available
Published Journal: Journal of Pakistan Medical Association, Volume: 65, Issue: 8, Year: 2015

Request the full text from PASTIC

More from Journal of Pakistan Medical Association
0

Citations

0

Downloads

54

Views

Copyright ©  PASTIC National Center, Islamabad www.pastic.gov.pk