OBJECTIVES: To assess the benefits and harms of routine abdominal drainage after Laparoscopic Cholecystectomy. STUDY DESIGN: A prospective observational study. PLACE AND DURATION: Department of surgery at Khyber Teaching Hospital, Peshawar from 1st Feb. 2009 to 30th April 2012 METHODOLOGY: The data of 300 patients who underwent laparoscopic cholecystectomy was analyzed. The patients were divided in two groups each of 150 patients. Group -A, included patients without drain and Group -B, included patients with drain. Operative and Post operative results of both groups were compared with regard to signs, symptoms, early and late complications and hospital stay using univariate analysis. RESULTS: Among total of 300 patients the male; female ratio was 1:3.The post op nausea (32%, n=48) and vomiting (18.6%, n=28) was less in patients without drain (group A). Whereas abdominal pain (22.6%, n=34) and shoulder tip pain (15.3% n=23) was less in patients with drainage tube (group B). Port site wound infection (11.3%, n=17) was more in group B. The hospital stay was less in the non drain group. CONCLUSION: Prophylactic drainage after a borderline case of laparoscopic cholecystectomy has found to be of no benefit rather it increases hospital stay and renders the patient prone to infections but it still remains a matter of individual preference.