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Relapsed diffuse large B-cell lymphoma treated by reduced-intensity allogeneic stem cell transplantation with donor lymphocyte infusion.

Author(s)
Qamar-Un-Nisa Chaudhry Department of Haematology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Parvez Ahmed Department of Haematology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Khalilulah Department of Haematology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Tariq Mehmood Satti Department of Haematology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Shahid Raza Department of Medical Oncology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Syed Kamran Mehmood Department of Medical Oncology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Mohammed Akram Department of Anaesthesiology, Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
Suhaib Ahmed Department of Haematology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan
Abstract
A 42 years old male with relapsed diffuse large B-cell lymphoma was given second-line chemotherapy followed by reduced intensity allogeneic stem cell transplantation from HLA matched brother. Twelve weeks posttransplant, his disease relapsed evidenced by the appearance of lymphoma cells in the peripheral blood and declining donor chimerism. Donor lymphocyte infusion was given that induced complete lymphoma remission. The patient is well 3 years posttransplant with his disease in complete remission.
Publication Details
Page(s) 211-213
DOI DOI not available
Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 20, Issue: 3, Year: 2010

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