Herbal medicines have long been the center of interest for the researchers. Herbs have long been used for the treatment of various ailments including diarrhea, ulcers, arthritis etc. people have always preferred herbal medicine believing it to be less toxic and inexpensive. Salvadora persica (miswak) is one of such plants which are used over the years mostly in the field of dentistry because of its religious significance in Islam. The purpose of this review is to go through the various medicinal properties of this plant. A literature search regarding this article was done on Google scholar and Pubmed /Medline during the time period 1988-2014.Most of the articles were related to oral health but few other properties are also found.