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Haplophytin B from Maclurodendron porter.

Author(s)
Muhammad Taher Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Deny Susanti Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Shafida Abd Hamid Department of Chemistry, Faculty of Science, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Khadijah Edueng Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Juliana Md Jaffri Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Anugerah Budipratama Adina Department of Pharmaceutical Technology, Faculty of Pharmacy, International Islamic University Malaysia, Jalan Sultan Ahmad Shah, Bandar Indera Mahkota, Pahang, Malaysia
Mohamad Fazlin Rezali SIRIM Berhad (National Metrology Laboratory), Lot PT 4803, Bandar Baru Salak Tinggi, Sepang, Selangor, Malaysia
Abstract
An alkaloid from Maclurodendron porteri has been isolated and characterized. Extraction process was conducted by acid-base extraction method followed by column chromatography. The structure was established by nuclear magnetic resonance spectroscopy and mass spectrometry. The compound was identified as haplophytin B which occurs commonly in the Rutaceae family. However, this is the first time this alkaloid was isolated and reported from the species. The compound showed no inhibition against Staphylococus aureus, Pseudomonas aeruginosa, Bacillus cereus and Escherichia coli and no cytotoxic activity against H199 and A549 cell lines.
Publication Details
Page(s) 179-181
DOI DOI not available
Published Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 27, Issue: 1, Year: 2014

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