Cardio vascular diseases are the most common cause of death in both eastern and western countries. Dyslipidemia and hypertension are included in cardiac risk assessment. Lipoprotein disorders in human may lead to coronary heart disease .The LDL-C/HDL-C ratio is more indicative of cardiovascular diseases than total cholesterol. High density lipoproteins have inverse relation with coronary heart disease. The present work illustrates, that five weeks oral administration of Anethum graveolens seeds aqueous extract has highly significant (0.01) reduction in body weight ,TC (total Cholesterol), TG(Triglyceride), LDL-C(low-density lipoprotein) ,LDL-C/HDL-C ratio and increase in HDL-C(high –density lipoprotein) in over weight rats as compare to control rats.