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Peritoneal dialysate IgG/C3 level-does it predict peritonitis?

Author(s)
Nisar Anwar Department of Nephrology & Department of Renal Medicine, Khyber Teaching Hospital, Peshawar, Pakistan, Manchester Royal Infirmary, UK
Alaister Hutchison Department of Nephrology & Department of Renal Medicine, Khyber Teaching Hospital, Peshawar, Pakistan, Manchester Royal Infirmary, UK
Ram Gokal Department of Nephrology & Department of Renal Medicine, Khyber Teaching Hospital, Peshawar, Pakistan, Manchester Royal Infirmary, UK
Abstract
Previous report have suggested that dialysate levels of 1gG and C3 correlate inversely with the likelihood of developing peritonitis. In a prospective study, we measured 1gG and C3 in the overnight dialysate (8-11 h dwell) in 34 CAPD patients over 24 months (monthly levels taken where possible.). During this period 24 patients had 1 or more episodes of peritonitis, and 10 had none. There were no significant differences between 1gG and C3 levels in the two groups at any time point, and large inter-patients and intra-patients variation in levels were seen. Dialysate levels of 1gG and C3 form the overnight dwell are not predictive of the risk of development CAPD peritonitis. Furthermore, no correlation was found between opsonin levels and onset of clinical peritonitis.
Publication Details
Page(s) 214-219
DOI DOI not available
Published Journal: Journal of Postgraduate Medical Institute, Volume: 18, Issue: 2, Year: 2004

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