Morphological changes induced by cotton seed flour in rat testes.

F. U. Wazir; I. U. Wazir; M. Javeed; Fida Muhammad; Saeed Jehanzeb Khan; S. Hamayun Shah

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Morphological changes induced by cotton seed flour in rat testes.

Author(s)

F. U. Wazir Department of Anatomy, Gomal Medical College, Dera Ismail Khan, Pakistan

I. U. Wazir Department of Anatomy, Gomal Medical College, Dera Ismail Khan, Pakistan

M. Javeed Department of Anatomy, Khyber Medical College, Peshawar, Pakistan

Fida Muhammad Department of Anatomy, Gomal Medical College, Dera Ismail Khan, Pakistan

Saeed Jehanzeb Khan Department of Anatomy, Khyber Medical College, Peshawar, Pakistan

S. Hamayun Shah Department of Anatomy, Gomal Medical College, Dera Ismail Khan, Pakistan

Abstract

Gossypol, a component of the cottonseed, has anti fertility effects. The present study was planned to determine whether diets containing whole cottonseed flour could produce morphological changes in the rat testes similar to pure gossypol. Sixteen animals were randomly divided into two groups, Control (C) and Test (T) groups. Each group comprised of o8 animals. Control group received standard diet, while test group received 7o% standard diet and 30% cottonseed flour. A significant decrease in body weight, testicular weight and diet consumption was seen in the test group. Histological sections were stained in serial order by three different stains, H&E, PAS and Masson`s Trichrome. Microscopic examination revealed significant increase in luminal diameter (P

Publication Details

Page(s) 105-109

DOI DOI not available

Published Journal: Biomedica, Volume: 22, Issue: 2, Year: 2006

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