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Adherence to antidepressants

Author(s)
Abimbola Farinde Department of Pharmacy, Clear Lake Regional Medical Center, 8201 W. Bellfort Houston, USA
Abstract
While major depression is considered a frequent mental illness there are ongoing reports of high non-adherence to antidepressant medications which places suffers at high risk for relapse, recurrence, or greater impairment,. The World Health Organization (WHO) defines adherence as the extent to which a person's behavior (e.g. taking medications) can align with the agreed recommendations of a health care provider. Unfortunately while patient may recognize the importance of adherence to antidepressant medications the majority of patients do not adhere to their prescribed antidepressants. Some of the factors that may contribute to or lead to non-adherence include knowingly or unknowingly missing doses, taking extra doses, delaying administration times, or taking drug holidays. Pharmacists have the unique ability to deter non-adherence through the performance of continuous assessment and monitoring of adherence in this population given these accessibility. Additionally, pharmacists are able to develop therapeutic alliances with patients that can help to increase the likelihood of achieving positive patient outcomes. Antidepressant non-adherence can be viewed as a significant public health concern so it is important for patients to be educated about the importance of adherence, and health care professionals should be aware of factors or patient characteristics that can serve as barriers to non-adherence.
Publication Details
Page(s) 44-47
DOI DOI not available
Published Journal: Archives of Pharmacy Practice, Volume: 4, Issue: 1, Year: 2013

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Keywords
Antidepressants, pharmacist’s role, Adherence
References
. .. [Last accessed on 2008]., : .
Edmunds MW,Mayhew MS .2009 .Pharmacology for the Primary Care Provider. , : .
.2000 .Diagnostic and Statistical Manual of Mental disorders. , : .
Sun G,Hsu M,Moyle W,Lin M,Creedy D .2011 .Mediating roles of adherence attitude and patient education on antidepressant use in patients with depression. Perspect Psychiatr Care, 47 : 13-22.
Thomas H,Chan T. Assessment .2011 .and management of depression in primary care settings. Nursing Older People, 24 : 32-40.
Maughan B,Collishaw S,Stringaris A .2013 .Depression in childhood and adolescence. J Can Acad Child Adolescent Psychiatry, 22 : 35-40.
Sclar D,Robison L,Schmidt J,Bowen K,Castillo L,Oganov A .2012 .Diagnosis of depression and use of antidepressant pharmacotherapy among adults in the United States. Clinical Drug Investig, 32 : 139-44.
Servellen G,Heise B,Ellis R .2011 .Factors associated with antidepressant medication adherence and adherence enhancement programmes: A systematic literature review. Mental Health In Family Med, 8 : 255-71.
Murata A,Kanbayashi T,Shimizu T,Miura M .2012 .Risk factors for drug nonadherence in antidepressant-treated patients and implications of pharmacist adherence instructions for adherence improvement. Patient Preference Adherence, 6 : 863-9.
.2003 .Adherence to Long-Term Therapies: Evidence for action. , : .
Sun G,Hsu M,Moyle W,Lin M,Creedy D .2011 .Mediating roles of adherence attitude and patient education on antidepressant use in patients with depression. Perspect Psychiatr Care, 47 : 13-22.
Prukkanone B,Vos T,Burgess P,Chaiyakunapruk N,Bertram M. .2010 .Adherence to antidepressant therapy for major depressive patients in a psychiatric hospital in Thailand. BMC Psychiatry, 10 : 64-8.
Pampallona S,Bollini P,Tibaldi G,Kupelnick B,Munizza C .2002 .Patient adherence in the treatment of depression. British Journal of Psychiatry, 180 : 104-9.
Chakraborty K,Avasthi A,Kumar S,Grover S. Attitudes .2009 .and beliefs of patients of first episode depression towards antidepressants and their adherence to treatment. Social Psychiatry Psychiatr Epidemiol, 44 : 482-8.
Geddes JR,Carney SM,Davies C,Furukawa TA,Kupfer DJ,Frank E .2003 .Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review. Lancet, 361 : 653-61.
Chong W,Aslani P,Chen T. .2011 .Effectiveness of interventions to improve antidepressant medication adherence: A systematic review. Int J Clin Pract, 65 : 954-75.
van Dijk L,Heerdink ER,Somai D,van Dulmen S,Sluijs EM,de Ridder DT .2007 .Patient risk profiles and practice variation in nonadherence to antidepressants, antihypertensives and oral hypoglycemics. BMC Health Services Res, 7 : 51.
Madsen J,McQuaid J,Craighead W. .2009 .Working with reactant patients: Are we prescribing nonadherence?. Depression Anxiety, 26 : 129-34.
Rubio-Valera M,Serrano-Blanco A,Travé P,Teresa Peñarrubia-María M,Ruiz M,Pujol M. .2009 .Community pharmacist intervention in depressed primary care patients (PRODEFAR study): Randomized controlled trial protocol. BMC Public Health, 9 : 284-91.
Machado M,Bajcar J,Guzzo GC,Einarson TR .2007 .Sensitivity of patient outcomes to pharmacist interventions: Part II: Systematic review and meta-analysis in hypertension management. Ann Pharmacother, 41 : 1770-81.
Demyttenaere K,Enzlin P,Dewe W,Boulanger B,De Bie J,De Troyer W .2001 .Adherence with antidepressants in a primary care setting, 1: Beyond lack of efficacy and adverse events. J Clin Psychiatry, 62 : 30-3.
Castle T,Cunningham M,Marsh G .2012 .Antidepressant medication adherence via interactive voice response telephone calls. Am J Manag Care, 18 : e346-55.
.2013 .How to cite this article: Farinde A. Adherence to antidepressants. Arch Pharma Pract, 4 : 44-6.
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