Rationale for Choosing the Basis for Early Coverage

Shmatenko Oleksandr; Kazmirchuk Anatolii; Solomennyy Andrii; Syrota Petro; Plieshkova Olga; Davtian Lena

doi:10.51847/g1ClUwBeV3

Author(s)

Shmatenko Oleksandr Ukrainian Military Medical Academy, Kyiv, Ukraine.

Kazmirchuk Anatolii Ukrainian Military Medical Academy, Kyiv, Ukraine.

Solomennyy Andrii Ukrainian Military Medical Academy, Kyiv, Ukraine.

Syrota Petro Ukrainian Military Medical Academy, Kyiv, Ukraine.

Plieshkova Olga Ukrainian Military Medical Academy, Kyiv, Ukraine.

Davtian Lena Ukrainian Military Medical Academy, Kyiv, Ukraine.

Abstract

Treatment of wounds of various genesis (surgical, purulent, gunshot wounds) remains a pressing problem today. Along with the improvement of treatment methods, the methods of combat operations are also being improved. At the same time, the change of approaches to traditional methods of wound treatment promotes the growth of resistant forms of microorganisms. All these complicate the treatment of wounds and the course of the wound process. For the treatment of wounds using a wide arsenal of drugs (antibiotics, local antiseptics) in various dosage forms (ointments, sprays, powders, solutions). Traditionally, the main elements of complex local therapy of wounds are antimicrobial drugs on a hydrophilic basis, in particular on a polyethylene glycol base with high osmotic activity. Therefore, the development of combined drugs with prolonged action with osmotic activity, which can absorb exudate but does not lead to the formation of a dry crust on the wound surface, is relevant.

Publication Details

Page(s) 103-108

DOI 10.51847/g1ClUwBeV3

Published Journal: Archives of Pharmacy Practice, Volume: 12, Issue: 1, Year: 2021

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Keywords

Diffusion, Polymer mass, Wounds, Excipients, Base

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