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Exploring the relationship between ABO blood groups and vulnerability to different diseases

Author(s)
Muhammad Imran Allama Iqbal Medical Collage, Jinnah Hospital,Lahore,Pakistan
Ramna Zia Department of Life Sciences, School of Science, University of Management and Technology,Lahore,Pakistan
Muhammad Aqib Fareed Allama Iqbal Medical Collage, Jinnah Hospital,Lahore,Pakistan
Benish Javed Allama Iqbal Medical Collage, Jinnah Hospital,Lahore,Pakistan
Ali Ahsan Graduate School of Science, Osaka Metropolitan University,Sugimoto, Sumiyoshi Ward Osaka-558- 0022,Japan
Kiran Jalil Graduate School of Science, Osaka Metropolitan University,Sugimoto, Sumiyoshi Ward Osaka-558- 0022,Japan
Muhammad Umer Khan Institute of Molecular Biology and Biotechnology, The University of Lahore,Lahore,Pakistan
Hassan Shabbir Chaudhry Department of Medicine and Surgery, Hijaz hospital Gulberg,Lahore,Pakistan
Muhammad Subaan Fareed Allama Iqbal Medical Collage, Jinnah Hospital,Lahore,Pakistan
Muhammad Muddassir Faculty of Science and Engineering, University of Engineering and Technology,,Pakistan
Chaudhry Ahmed Shabbir Allama Iqbal Medical Collage, Jinnah Hospital,Lahore,Pakistan
Zahra Kalim Institute of Microbiology, Government College University,Faisalabad,Pakistan
Abstract
The ABO grouping of blood, comprising the four main types A, B, AB, and O, has been widely recognized for its significance in establishing the suitability of organ transplants and blood transfusions. Recent research has revealed the potential influence of ABO blood types on susceptibility to certain diseases. The current study uses an extensive review of the body of literature and epidemiological investigations to explore the relationships between ABO blood types and disorders that impact various organ systems. The focus lies on chronic ailments, encompassing certain types of cancer as well as cardiovascular, gastrointestinal, and infectious disorders. For example, those with A blood group may exhibit a higher susceptibility to developing peptic carcinoma, whereas individuals with blood type O may demonstrate a lower propensity for cardiovascular issues. The fundamental mechanisms of these interactions remain incompletely understood. The potential causes for the impact of ABO antigens on immunological responses, coagulation factors, inflammation, and interactions with pathogens are still under investigation. The presence of genetic and molecular variations within ABO blood types may contribute to differing susceptibilities to illnesses. This review examines the correlation between ABO blood types and susceptibility to diseases.
Publication Details
Page(s) 1-16
Published Journal: Asian Journal of Agriculture and Biology, Volume: 4, Issue: 0, Year: 2024

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Keywords
malaria, Malaria, cancer, infectious disease, Hypertension, ABO blood groups, cardiovascular disease, Malaria
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