C-reactive protein and statins.

Bibi Kulsoom; S. Nazrul Hasnain

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C-reactive protein and statins.

Author(s)

Bibi Kulsoom Department of Biochemistry, Ziauddin Medical College, Ziauddin University, Karachi, Pakistan

S. Nazrul Hasnain Department of Biochemistry, Ziauddin Medical College, Ziauddin University, Karachi, Pakistan

Abstract

Atherosclerosis is now widely considered as a form of inflammatory disorder rather than merely a consequence of dyslipidemia. C-reactive protein (CRP) is an acute phase reactant, seen elevated in case of ongoing inflammation. Measuring both CRP and cholesterol provide a more accurate indication of risk than cholesterol estimation alone. It is observed that lipid lowering drugs reduce the incidence of coronary events and stroke. This is mainly due to the pleiotropic action which is independent of their hypolipidemic action. In this review article, recent developments regarding the role of statin therapy in prevention of adverse cardiovascular events is discussed succinctly.

Publication Details

Page(s) 49-54

DOI DOI not available

Published Journal: Pakistan Journal of Pharmacology, Volume: 23, Issue: 2, Year: 2006

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