No Detail Found!

Community-acquired Methicillin-resistant Staphylococcus Aureus Pneumonia: A Diagnostic Challenge

Author(s)
Muhammad Nadeem Ahmed khan Department of Medicine, Bahria University Medical and Dental College,Karachi,Pakistan
Sana Jabeen Department of Medicine, Memon Medical Institute,Karachi,Pakistan
Shaheena Begum Department of Medicine, Sindh Government Hospital,Karachi,Pakistan
Hera Nadeem Bhitai Dental and Medical College,Mirpur Khas,Pakistan
Abstract
Even though methicillin-resistant Staphylococcus aureus (MRSA) is considered a source of nosocomial pneumonia, a few cases have likewise depicted instances of community-acquired pneumonia (CAP) among healthy individuals that were caused by MRSA. Mostly CA-MRSA causes skin and soft tissue infection but can be responsible for severe invasive infection with higher morbidity. Invasive CA-MRSA requires aggressive management to prevent complications. CA-MRSA strains are now recognized as distinct clonal entities that difer from traditional hospital-acquired MRSA (HA-MRSA) strains. The increasing prevalence of MRSA in the community is an important public health problem, which needs increased vigilance in the diagnosis and management of suspected and confirmed staphylococcal infections.We present an intense case of CAP brought about by MRSA with impending respiratory failure in a 19-year-old male, who presented with acute febrile illness with swelling over lips with no co-morbid and insignificant past medical history. Through this case, we intend to increase awareness among physicians about the growing role of CA-MRSA in the population; they should be meticulous in treating patients with CA-MRSA, and be aware of the complications of this disease and the appropriate empiric and target antibiotics regimen for such infections, whenever it is suspected, to enhance better clinical outcomes
Publication Details
Page(s) 184-187
Published Journal: Liaquat National Journal of Primary Care, Volume: 6, Issue: 2, Year: 2024

Request the full text from PASTIC

Keywords
Febrile illness, community-acquired pneumonia, Methicillin-resistant Staphylococcus aureus (MRSA)
References
Xia H,Gao J,Xiu M,Li D .2020 .: e20914. Medicine. Medicine (Baltimore), 99(26) : 0000000000020914.
Aliberti S,Reyes LF,Faverio P,Sotgiu G,Dore S,Rodriguez AH .2016 .Global initiative for meticillin-resistant Staphylococcus aureus pneumonia (GLIMP): an international, observational cohort study. Lancet Infect Dis, 3099(16) : 30267-5.
Self WH,Wunderink RG,Williams DJ,Zhu Y,Anderson EJ,Balk RA .2016 .Staphylococcus aureus community-acquired pneumonia: prevalence, clinical characteristics, and outcomes. Clin Infect Dis, 63(3) : 300-9.
David MZ,Daum RS .2010 .Community-associated methicillin-resistant Staphylococcus aureus: epidemiology and clinical consequences of an emerging epidemic. Clin Microbiol Rev, 23(3) : 09-87.
Mandell LA,Wunderink R .2012 .Methicillin-resistant Staphylococcus aureus and community-acquired pneumonia: an evolving relationship. Clin Infect Dis, 54(8) : 1134-6.
Francis JS,Doherty MC,Lopatin U,Johnston CP,Sinha G,Ross T .2005 .Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis, 40(1) : 100-7.
Gillet Y,Issartel B,Vanhems P,Fournet JC,Lina G,Bes M .2002 .Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet, 6736(02) : 07877-7.
.2021 .8. Clinical and Laboratory Standards Institute. M100 Performance Standards for Antimicrobial Susceptibility Testing. , 31(1) : .
.2019 .Breakpoint tables for interpretation of MICs and zone diameters. Version 9.0, : .
Yonezawa R,Kuwana T,Kawamura K,Inamo Y. .2015 .Invasive community-acquired methicillin-resistant Staphylococcus aureus in a Japanese girl with disseminating multiple organ infection: a case report and review of Japanese pediatric cases. Case Rep Pediatr, : 291025.
Lobo LJ,Reed KD,Wunderink RG .2010 .Expanded clinical presentation of community-acquired methicillin-resistant Staphylococcus aureus pneumonia. Chest, 138(1) : 1562-6.
Hidron AI,Low CE,Honig EG,Blumberg HM .2009 .Emergence of community-acquired meticillin-resistant Staphylococcus aureus strain USA300 as a cause of necrotising community-onset pneumonia. Lancet Infect Dis, 3099(09) : 70133-1.
Naimi TS,LeDell KH,Como-Sabetti K,Borchardt SM,Boxrud DJ,Etienne J .2003 .Comparison of community- and health careassociated methicillin-resistant Staphylococcus aureus infection. JAMA, 290(22) : 2976-84.
Buck JM,Como-Sabetti K,Harriman KH,Danila RN,Boxrud DJ,Glennen A .2005 .Community-associated methicillin-resistant Staphylococcus aureus. Emerg Infect Dis, 11(10) : 1532-8.
Gould FK,Brindle R,Chadwick PR,Fraise AP,Hill S,Nathwani D .2009 .) for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the United Kingdom. J Antimicrob Chemother, 63(5) : 849-61.
Liu C,Bayer A,Cosgrove SE,Daum RS,Fridkin SK,Gorwitz RJ .2011 .Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis, 52(3) : e18-55.
Blot S,Koulenti D,Akova M,Bassetti M,De Waele JJ,Dimopoulos G .2014 .3): R99. Crit Care, 18 : .
0

Citations

0

Downloads

58

Views