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CS-1545: Large Language Models for Early Crop Disease Detection: Decoding RNA-Seq Linguistic Signals

Author(s)
Shehr Bano Namal University,Mianwali, Pakistan.
Muzamil Ahmed Namal University,Mianwali, Pakistan.
Ahmed Salim Namal University,Mianwali, Pakistan.
Abstract
Agriculture is the backbone of Pakistan, a country of 255 million. Amongseveral challenges of the traditional agricultural system, delayed diseasedetection is one of the major concerns causing low annual yield and crop losses.Pakistani farmers still depend on visual symptoms that emerge only afterirreversible damage. To address these concerns, we propose a novelcomputational approach for early plant disease detection by treating RNAexpression patterns as a computational linguistic problem. The BioLingual™algorithm will apply advanced natural language processing (NLP) techniques toRNA-seq data to identify disease signatures up to three weeks before visiblesymptoms appear. Our pipeline will integrate already extracted RNA sequencesfrom field samples, state-of-the-art analytics for pattern recognition, and thecreation of Pakistan's first crop disease biomarker database. Initially targetingwheat crops, upon receiving sequencing/qPCR that are plant pathogenindicators, our bidirectional sequence modeling and self-attention approachextracts disease patterns from enriched RNA, outperforming traditional visualinspection for early disease detection, avoiding complex bioinformatics. Theproject’s outcomes will strengthen national food security, enhance economicresilience, and position Pakistan as a leader in AI-enabled agriculturalbiotechnology.
Publication Details
Page(s) 101-101
DOI DOI not available
Published Journal: 4th International Conference of Sciences “Revamped Scientific Outlook of 21st Century, 2025” , November 12,2025, Volume: 1, Issue: 1, Year: 2025

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Keywords
natural language processing, Early Disease Detection, RNA expression analysis, biomarker identification, computational linguistics, plant pathology
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