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Lactation and serum prolactin.

Author(s)
Rafique Ahmad Khan Department of Physiology, University College of Medicine, The University of Lahore, Pakistan
Bilquees Akhtar Department of Cardiology, King Edward Medical College and Mayo Hospital, Lahore, Pakistan
Ghulam Hussain Department of Pathology, King Edward Medical College, Lahore, Pakistan
Shahnaz Javed Khan Department of Pathology, King Edward Medical College, Lahore, Pakistan
Muhammad Sulaman Khan Sheikh Zaid Hospital, Rahim Yar Khan, Pakistan
Abstract
Prolactin belongs to the family of structurally similar somatomamotropic hormones like growth hormone (GH). It is secreted mainly by the pituitary Lactotrophs from the posterolateral aspect of adenohypophysis as a single polvpeptide. The secretion of prolactin from anterior pituitary is mainly under tonic inhibition from dopaminergic cells in hypothalamus. Nursing is potent stimulus to prolactin secretion. The suckling stimulus from the baby is the most powerful signal to increase prolactin secretion. The objective of this study was to determine the relationship to serum Prolactin levels with lactational amenorrhea. Methods: The serum Prolactin levels were determined in 30 mensturating lactating females (Controls) and 30 amenorrheic lactating females (Study group) by using the radioimmunoassay (RIA). Results: The mean values of prolactin levels were significantly increased (P
Publication Details
Page(s) 60-63
DOI DOI not available
Published Journal: Pakistan Postgraduate Medical Journal, Volume: 18, Issue: 2, Year: 2007

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