Pattern of subclinical thyroid disease

Aamir Ijaz; Munnawar Hussain Marri; Ayaz Hussain Qureshi; Muhammad Ashraf Qamar; Nadir Ali

Author(s)

Aamir Ijaz Department of Pathology, Army Medical College, Rawalpindi - Pakistan.

Munnawar Hussain Marri Department of Pathology, Combined Military Hospital, Quetta.Pakistan

Ayaz Hussain Qureshi Department of Pathology, Army Medical College, Rawalpindi - Pakistan.

Muhammad Ashraf Qamar Department of Pathology, Combined Military Hospital, Quetta.Pakistan

Nadir Ali Department of Pathology, Combined Military Hospital, Quetta.Pakistan

Abstract

To evaluate the prevalence of subclinical thyroid disease (SCTD) in local population visiting a hospital laboratory for thyroid function tests. Design: It was a hospital - based study carried in consecutive patients who reported for thyroid function tests in the hospital laboratory. Place and Duration of Study: The study was conducted in Combined Military Hospital, Quetta during June 1999 to September 2000. Subjects and Methods: Serum samples of 917 patients living in Quetta and its surrounding were analysed for thyroid stimulating hormone (TSH), free thyroxine (FT4), and total tri-iodothyronine (T3) concentration using chemiluminescence technique on hormone autoanalyser (LIA-Mat - Sangtech Germany). Results: Out of 917 patients, 287 (23%) were found to be having SCTD while overt thyroid disease was found in 288 (31 %) patients. Prevalence of sub-clinical hypothyroidism (SCO) and sub-clinical hyperthyroidism (SCE) was found to be almost equal with a profound female preponderance in both the groups. SCO was more common in children (<12 years of age). Conclusion: Almost every fourth patient reporting for thyroid function tests was diagnosed as having SCTD - a disease entity that is still not well known and that poses diagnostic and management problems for the pathologists and clinicians.

Publication Details

Page(s) 86-88

DOI DOI not available

Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 12, Issue: 2, Year: 2002

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Keywords

Hyperthyroidism, Hyperthyroidism, hypothyroidism, Thyrotropin, Thyroid diseases, Thyroid Function Tests

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