Prognostic factors in typhoid perforation

Muzaffar Aziz; Abdul Qadir; Muzammil Aziz; Faizullah

Author(s)

Muzaffar Aziz Department of Surgery, Nishtar Hospital, Multan. Pakistan

Abdul Qadir Department of Surgery, Nishtar Hospital, Multan. Pakistan

Muzammil Aziz Department of Surgery, Nishtar Hospital, Multan. Pakistan

Faizullah Department of Surgery, Nishtar Hospital, Multan. Pakistan

Abstract

Objective: To discuss the effect of duration of illness before perforation and time interval between perforation and surgery on the prognosis of typhoid perforation. Design: Comparative study. Place and Duration of Study: Nishtar Hospital, Multan from September 2002 to September 2004. Patients and Methods: Seventytwo patients of typhoid perforation were included in this study. The patients were divided into three groups A, B and C according to duration of illness before perforation. In these groups, typhoid perforation occurred during 1st, 2nd and 3rd week respectively. Further patients were divided into group D, E and F according to time interval between perforation and surgery. In these groups surgery was carried out within 24 hours, 24-48 hours and after 48 hours respectively. Results: Fiftysix patients were males and 16 were females. In groups A, B and C, mortality rate was 6.6%, 13.3% and 25%, while morbidity rate was 33.3%, 55.5% and 75% respectively. There were 12, 42 and 18 patients in Group D, E and F with mortality rate of 8.33%, 11.9% and 22.2% respectively. Group D had 41.6% morbidity rate while group E and F had 71.42% and 77.7% respectively. Conclusion: In this study, early perforation during the typhoid fever and short perforation-operation interval were good prognostic signs. So best results can be achieved by early patient`s presentation and early operation.

Publication Details

Page(s) 704-707

DOI DOI not available

Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 15, Issue: 11, Year: 2005

Request the full text from PASTIC

Keywords

Mortality, Morbidity, prognosis, Typhoid, Intestinalperforation

References

.1983 .. Typhoid perforatoiofnthe intesti Arch Surg, 118 : 1269-71.

Cameron FS .1990 .Typhoid perforation of the Heun A reviewof59 cases. hop GeogrMed, 42 : 330-6.

.2001 .Postgrad cases. Pediatric Surg Int, 60 : 523-9.

.2003 .Sharma a ruraAlfricanhospitaWle. st AfrJMed, 15 : 205-8.

Pai D .2001 .. ap Gastroenterol, 22 : 155-8.

.2004 .. AmJEpidemiol, 160 : 46-50.

Kaul BK .1975 .. t Surg, 60 : 407-10.

Shah JS .1967 .Typhoid perforatioanr:eviewof40 cases. J Assoc Physicians India, 15 : 155-8.

.1975 .Typhoid perforation treatebdy closuraend proximalside toside ileotransverse colostomJyIn. dian MedAssoc, 65 : 297-9.

Hadly GP .1984 .The surgicamlanagemenotftyphoid perforatiniocnhildrenB. rjSurg, 71 : 928-9.

Bac B .1995 .. rg, 88 : 1512-5.