Comparison between modified and conventional combined Trabeculotomy-Trabeculectomy with Mitomycin-C for intraocular pressure reduction in primary congenital glaucoma

Ahmed Raza; Muhammad Ajmal Chaudhary; Asma Mushtaq; Asad Aslam Khan

doi:10.12669/pjms.40.9.8788

Author(s)

Ahmed Raza Department of Pediatric Ophthalmology, The University of Child Health Sciences, Lahore, Pakistan.

Muhammad Ajmal Chaudhary Department of Pediatric Ophthalmology, Sheikh Zayed Medical College,Rahim Yar Khan,Pakistan

Asma Mushtaq Department of Pediatric Ophthalmology, The University of Child Health Sciences, Lahore, Pakistan.

Asad Aslam Khan Department of Ophthalmology, COAVS/KEMU, Lahore, Pakistan.

Abstract

Objectives: To determine the eficacy of modified combined trabeculotomy-trabeculectomy (CTT) with mitomycin-C (MMC) versus conventional CTT with MMC for intraocular pressure (IOP) reduction in patients with primary congenital glaucoma (PCG). Methods: This interventional study was carried out in The Institute of Ophthalmology, Lahore from January 2018 to June 2019. We included 70 patients of either gender, with the age range from birth to ten years and with PCG having IOP >30 mm Hg. These patients were divided in groups A and B with 35 patients in each group. Patients in Group-A underwent modified CTT with MMC and in Group-B conventional CTT with MMC was carried out. Results: The mean age of our patients was 15.17 ± 12.39 months. Regarding gender, 57 (81.4%) were males and 13 (18.6%) were females. Baseline mean IOP in Group-A was 32.49 ± 1.01 mm Hg whereas in Group-B mean IOP was 31.97 ± 1.04 mm Hg. After one month, the mean IOP was 27.60 ± 1.72 mm Hg in Group-A, whereas mean IOP was 27.40 ± 1.82 mmHg in Group-B. After three months, the mean IOP was 21.63 ± 1.09 mm Hg in Group-A, whereas 20.97 ± 1.12 mm Hg in Group-B. In Group-A eficacy was achieved in 14 (40%) patients whereas in Group-B eficacy was achieved in 25 (71.4%) patients. Conclusion: Our study revealed that conventional CTT with MMC showed better eficacy than modified CTT with MMC for reduction of IOP in PCG.

Publication Details

Page(s) 1937-1940

DOI 10.12669/pjms.40.9.8788

Published Journal: Pakistan Journal of Medical Sciences, Volume: 40, Issue: 9, Year: 2024

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Keywords

Primary congenital glaucoma, Trabeculectomy, Trabeculotomy, Combined trabeculotomy- trabeculectomy and Pediatric glaucoma surgery

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