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Potential Hematological Predictors Assessing Severity in Patients Presenting with Dengue

Author(s)
MARIA SATTAR Forensic Medicine, HITEC-IMS, Taxila – Cantt., Pakistan
ZUHA ALI Department of Pathology, HITEC-IMS, HIT, Taxila – Cantt., Pakistan
NADIA KASHIF Jinnah Medical College/ District Specialist Naseerullah Babar Memorial Hospital, Peshawar, Pakistan
SHAHIDA MUSHTAQ Department of Pathology, HITEC-IMS, Taxila – Cantt., Pakistan
AMBREEN ZAFAR Department of Pathology, HITEC-IMS, Taxila – Cantt., Pakistan
NAZIA SIDDIQUI Department of Pathology, HITEC-IMS, Taxila – Cantt., Pakistan
Abstract
Aim: To determine the potential hematological predictors and biochemical markers for assessing severity in patients presenting with dengue Methods: This descriptive study was conducted at Jinnah Medical College/ District Specialist Naseerullah Babar Memorial Hospital, Peshawar in the duration from March, 2022 to August, 2022 on 150 Dengue NS1 (ICT) positive patients. Hematological and biochemical markers were assessed among severe vs non-severe dengue fever patients. Hematological and biochemical markers were assessed by T-test with P < 0.05 as significant. Results: Hematocrit (%), AST (U/L) and ALT (U/L) levels were higher significantly in the severe dengue patients' vs non-severe dengue fever patients, platelet (mcL) and White blood cells (mcL) were significantly lower in the severe dengue patients' vs nonsevere dengue fever patients. Conclusion: We conclude that Hematocrit (%), platelets count, White blood cells, Alanine transaminase (ALT) (U/L) and Aspartate aminotransferase (AST) (U/L) and are important hematological and biochemical predictors for assessing the severity of dengue.
Publication Details
Page(s) 366-368
DOI 10.53350/pjmhs2023171366
Published Journal: Pakistan Journal of Medical and Health Sciences, Volume: 17, Issue: 1, Year: 2023

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Keywords
Dengue fever, severity, biochemical markers, Hematological markers
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