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Proliferative Verrucous Leukoplakia with Dysplastic Changes

Author(s)
Sanaa Ahmed Department of Oral Medicine/Surgery, Jinnah Sindh Medical University, Pakistan
Muhammad Nasir Dentistry, Jinnah Sindh Medical University, Pakistan
M. Sibghatullah Khan Department of Oral Medicine/Surgery, Jinnah Sindh Medical University, Pakistan
Maria Naz Department of Oral Medicine/Surgery, Jinnah Sindh Medical University, Pakistan
Uzma Bukhari Department of Pathology, Dow University of Health Sciences, Pakistan
Abstract
Proliferative verrucous leukoplakia is one of the rare premalignant white lesions with highest conversion rate to malignancy. It grows gradually and irreversibly with multifocal presentation, exophytic and verrucous appearance. This lesion has been reported resistant to all therapeutic approaches including both non-surgical and surgical. Predisposing factors include female gender in the 6th decade of life. Proliferative verrucous leukoplakia has the highest tendency to neoplastic transformation and progression to oral squamous cell carcinoma and oral verrucous carcinoma in majority of the cases. The case of proliferative verrucous lesion clinically appearing benign presented here but on histopathology proven dysplasia in a patient with the history of smoking which he stopped six years back.
Publication Details
Page(s) 172-174
DOI 10.51985/JBUMDC202238
Published Journal: Journal of Bahria University Medical and Dental College, Volume: 12, Issue: 3, Year: 2022

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