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Percutaneous Image-Guided Microwave Ablation for Treating Postsurgical Intrapulmonary Oligometastases or Oligorecurrence

Author(s)
Qi-Ming Zheng Department of Thoracic Surgery, Jinan Central Hospital, Shandong University, Jinan, China; Department of Thoracic Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan, China
Yuan-Yuan Li Department of Oncology, Jinan Central Hospital, Shandong University, Jinan, China
Tai-Yang Zuo Department of Oncology, Jinan Central Hospital, Shandong University, Jinan, China
Chun-Hai Li Department of Radiology, Qilu Hospital of Shandong University, Jinan, China
Zhi-Gang Sun Department of Thoracic Surgery, Jinan Central Hospital, Shandong University, Jinan, China;Department of Thoracic Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan, China
Abstract
Objective: To assess the clinical e cacy of microwave ablation (MWA) in treating tumour patients with postsurgical intrapulmonary oligometastases or oligorecurrence (PIORO). Study Design: Descriptive study. Place and Duration of the Study: Departments of Thoracic Surgery and Oncology, Jinan Central Hospital and Qilu Hospital, Jinan, China, from January 2014 to June 2023. Methodology: Clinical data of 31 patients with PIORO receiving treatment with MWA were retrospectively analysed. After undergoing MWA, the patients were followed up for computed tomography (CT) examination on the 7th day, 1st month, and every 3 months, respectively. The Kaplan-Meier method was conducted to evaluate the clinical outcomes; overall survival (OS), progression-free survival (PFS), and time to local progression (TTLP). Results: All patients with PIORO were successfully treated with MWA. The 3-year survival rate of patients was 35.5%. The median OS was 26.0 months, the median PFS was 11.1 months, and the median TTLP was 14.4 months. Patients with oligometastatic or oligorecurrent tumours d3 cm in diameter showed better PFS (d3 cm, 14.261 m vs. >3 cm, 7.786 m; p 3 cm, 12.214 m; p 3 cm in diameter. Clinical characteristics of the patients were not signi cantly correlated with OS. Conclusion: MWA, as a topically therapeutic method, is an e ective procedure for tumour patients with PIORO, especially in cases of oligometastatic or oligorecurrent tumours d3 cm in diameter.
Publication Details
Page(s) 178-182
Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 34, Issue: 2, Year: 2024

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Keywords
Thermal ablation, Microwave ablation, survival, Progression-free survival, Oligometastases, Oligorecurrence
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