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Effect of Chronic kidney disease on Thyroid function

Author(s)
Furqan Arshad Spal DMLS Scholar, Department of Allied Health Sciences, the University of Lahore, Gujrat Campus,,Pakistan
Mahnoor Fatima Department of Allied Health Sciences, the University of Chenab,Gujrat,Pakistan
Abid Ali Department of Allied Health Sciences, the University of Chenab,Gujrat,Pakistan
Umair Waqas Idrees Institute of Rehabilitation Sciences,Sialkot,Pakistan
Hannana Maryam Department of Allied Health Sciences, University of Chenab,Gujrat,Pakistan
Zaheer Abbas Department of Allied Health Sciences, the University of Chenab,Gujrat,Pakistan
Abstract
Background: Chronic kidney disease results in downturn of glomerular filtration rate, which brings about nephropathic effect. The intensifying nephropathy muddles the thyroid functions and turns down the iodide clearance, thus expedites the hypothyroidism. Objective: The study aimed to link chronic kidney disease with hypothyroidism. Material and Methods: Our study design was cross-sectional. Chronic kidney disease patients were selected for thyroid profile (triiodothyronine, thyroxine and thyroid stimulating hormone) testing. Statistical analysis was consummated on collected data, to check out the correlation between CKD and hypothyroidism. Results: We enrolled 105 patients suffering from CKD. Of them 62 were male patient and 43 were female. Our analysis concluded that 49, of whom 30 were male and 19 were female, had hypothyroidism. 23; 16 male and 7 female, were having subclinical hypothyroidism and low T3 was seen in 33 individuals, comprising of 16 male and 17 female patients. Conclusion: It is evident that there is substantial effect of CKD over thyroid function, as hypothyroidism, subclinical hypothyroidism and low T3 syndrome are more frequent in CKD patients. To fend off CKD, the thyroid function needs to be kept under observation, so that a good prognosis could be gained.
Publication Details
Page(s) 38-41
DOI DOI not available
Published Journal: BMC journal of Medical Sciences, Volume: 4, Issue: 2, Year: 2023

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Keywords
Chronic kidney disease, Thyroid Stimulating Hormone, Subclinical Hypothyroidism, throxine, Glomerular filtration rate
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