Gliosarcoma: An uncommon brain tumor.

Rafael Cincu; Jose Luis Capablo Liesa; Jose Eiras

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Gliosarcoma: An uncommon brain tumor.

Author(s)

Rafael Cincu Departments of Neurosurgery and Neurology, Miguel Servet University Hospital, Zaragoza, Spain

Jose Luis Capablo Liesa Departments of Neurosurgery and Neurology, Miguel Servet University Hospital, Zaragoza, Spain

Jose Eiras Departments of Neurosurgery and Neurology, Miguel Servet University Hospital, Zaragoza, Spain

Abstract

Gliosarcomas are rare bimorphic intraaxial malignant neoplasms of the central nervous system. A 69-year-old gentleman presented with a history of right-sided weakness and slurred speech. Brain imaging (CT scan and MRI) was suggestive of a left fronto-parietal mass lesion with contrast enhancement at the periphery. Neuropathological examination revealed a malignant brain tumour presenting a biphasic tissue pattern with gliomatous and mesenchymal components suggestive of gliosarcoma that was further evaluated immuno¬histochemically. Although the treatment of gliosarcomas is almost similar to glioblastomas (surgical resection and, depending on clinical status, radiotherapy and/or chemotherapy) the prognosis of gliosarcomas remains poor.

Publication Details

Page(s) 20-22

DOI DOI not available

Published Journal: Pakistan Journal of Neurological Sciences, Volume: 4, Issue: 1, Year: 2009

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