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Comparison Between Shear Wave Elastography and Serological Findings for Evaluation of Fibrosis in CLD Patients

Author(s)
MAHJABEEN LIAQAT Department of Radiological sciences and Medical Imaging Technology, University of Lahore, Pakistan
RAHAM BACHA Department of Radiological sciences and Medical Imaging Technology, University of Lahore, Pakistan
KASHIF SIDDIQUE Department of Radiology, Shaukat Khanum Hospital,Lahore-,Pakistan
MEHREEN FATIMA Department of Radiological sciences and Medical Imaging Technology, University of Lahore,,
IMRAN YOUSAF Department of Radiology, Shalamar Hospital Lahore ,Pakistan
SYED AMIR GILANI Department of Radiological sciences and Medical Imaging Technology, University of Lahore, Pakistan
TALHA LAIQUE Department of Pharmacology, Allama Iqbal Medical College,Lahore,Pakistan
Abstract
Background: With advancement in the field of medicine yet there is a need of non-invasive method for detecting fibrosis in patients suffering from chronic liver disease. Aim: To find an agreement between Shear Wave Elastography and APRI & FIB-4 score in patients of CLD. Study design: Descriptive, cross-sectional. Methodology: The current project was conducted at department of Radiology, Shaukat Khanum Hospital, Lahore from 01-06-2019 to 1-12-2019. Current study comprised of 80 patients of both genders. Stages of fibrosis were defined on SWE. FIB-4 and APRI score were determined using serological markers. The collected data was analyzed by using SPSS version 24. Mean with standard deviation was calculated for age, AST, ALT, Platelet count. Results: In our study, 62.5% were males while 37.5% were females. With mean age of 43.47 SD±13.85. APRI & FIB-4 scores predicted F4 patients using cutoff values of 0.47 (Sn. 72%, Sp. 70%) and 1.27 (Sn. 78%, Sp. 73%) respectively. Conclusion: The diagnostic accuracy of FIB-4 for predicting liver fibrosis was better than that of APRI in all stages of liver fibrosis when compared with SWE.
Publication Details
Page(s) 495-497
DOI DOI not available
Published Journal: Pakistan Journal of Medical and Health Sciences, Volume: 15, Issue: 1, Year: 2021

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Keywords
Liver fibrosis, APRI, FIB-4, Chronic Liver Disease and Shear Wave Elastography.
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