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Frequency of Thyroid Dysfunction in Melasma Patients

Author(s)
HINA MEHMOOD Department of Dermatology, Jinnah Hospital,Lahore-,Pakistan
SUMMAYAH NIAZI Department of Physiology, Fazaia Medical College,Islamabad-,Pakistan
MUHAMMAD JABRAN JAVAID Department of Physiology, Sialkot Medical College,Sialkot-,Pakistan
MAIMONA TABBSUM Department of Physiology, Akhtar Saeed Medical and Dental College,Lahore-,Pakistan
MUHAMMAD BAHADUR BALOCH Department of Anatomy, Shalamar Medical and Dental College,Lahore-,Pakistan
RIZWAN AHMAD Department of Ophthalmology, General Hospital,Lahore-,Pakistan
TALHA LAIQUE Department of Anatomy, Shalamar Medical and Dental College,Lahore-,Pakistan
Abstract
Background: Symmetrical hyper-pigmentation on the face is the characteristic of melasma. Aim: In current project, goal was to determine the frequency of thyroid dysfunction in melasma patients of a tertiary care hospital. Study design: It was a a cross-sectional study. Methodology: With the sample size of 150 melasma patients, current study was carried out from September 2017 to March 2018 at the department of Dermatology, Jinnah Hospital, Lahore following the approval by Hospital's Ethical Committee. Early morning blood sample was taken from all enrolled patients fulfilling the inclusion criteria and sent to the lab for thyroid function test (FT4 and TSH). Thyroid dysfunction was categorized as hypothyroidism and hyperthyroidism. Data was entered and analyzed by Statistical Package for Social Sciences (SPSS software, version 21). Chi-square test was applied as p-value = 0.05 was considered significant. Results: In present study, patients (n=150) of both genders were included with the age (18-50 years ) having a mean ± SD of 31.07±8.91 years. Among 150 patients, duration of melasma ranged from 1-6 years Results showed 29 (19.3%) had thyroid dysfunction among 150 patients. Majority cases were sub-clinically hypothyroid. Conclusion: Thyroid dysfunction can be associated with melasma which can be sub-clinically hypothyroid.
Publication Details
Page(s) 692-694
DOI DOI not available
Published Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 2, Year: 2020

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Keywords
Melasma, Hypothyroid and Hyperthyroid, Thyroid Function Tests
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