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Effectiveness of pharmaceutical drugs to Decrease blood pressure: Meta-Analysis study

Author(s)
MILAD MAHMOUDABADI Emergency Unit, HSE Department , Gol Gohar Industrial And Mining Co, Sirjan, Iran
MINA SADAT MOHAJERZADEH HEIDARI Department of Radiology. Faculty Of Medicine. North Khorasan University of Medical Sciences, Bojnurd, Iran
PARMIS GHAZI HOSSEINI Department of Radiology. Faculty of Medicine. Mashad University of Medical Sciences, Mashad, Iran
MARIEH ALIZADEH Emergency Unit, HSE Department , Gol Gohar Industrial And Mining Co,Sirjan,Iran
FATEMEH MALEKI Department Of Emergency Medicine, Faculty of Medicine, Birjand University Of Medical Sciences, Brjand, Iran
MOHSEN EBRAHIMI Department of Emergency Medicine. Faculty of Medicine. Mashhad University of Medical Sciences, Mashhad, Iran
Abstract
Background: In the past few decades, studies have increased in the area of blood pressure, its causes and effective treatments, so revision and combination of pharmaceutical and non-pharmaceutial treatments are considered important in this study. Aim: To quantify effectiveness of combinational studies in the area of specific treatments related to blood pressure and to quantify effectiveness of combinational studies. Method: Meta-analysis is method used in this study. Scholar used findings of 21 studies with 75 effect sizes. Meta-analysis studies indexed in country database were the statistical society. Sample was chosen by purposive method based on inclusion and exclusion criteria and CMA2 soft-wares were used to analyse data. Funnel diagram, safe indicator of destruction, intercepts of Iger regression and correlation of tao kendall ranks applied to investigate bias of diffusion. Combinational sizes was calculated based on two random models, Q indicators and I square was used to analyse in homogeneity. Results: Quantity of combinational effect are 33/0 and 30/0 in constant and random models respectively. This amount is considered moderate based on chosen index. Existence of moderator variables was confirmed based on inhomogeneity analysis results. Results showed that other factors affect quantity and process of hypertension beside drugs. Conclusion: All treatments that are used to control blood pressure, prevent from cardiovascular and other diseases too. Checking blood pressure should be considered to examine impact of these treatments.
Publication Details
Page(s) 467-473
DOI DOI not available
Published Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 1, Year: 2020

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Keywords
hypertension meta-analysis pharmaceutical drugs
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