Analysis and design of e-office application on ministry health of Republic of Indonesia based on microservice architecture. The system is converting from monolithic architecture into microservice architecture by using domain driven design framework to breaking the domain business of the system. Microservice architecture is an important part to agile, resilience, and high-availability. By improvement the feature and the high intention to use to the system by regulation of e-government of Republic of Indonesia at Ministry bureaucracy. By using the Microservice Architecture will improve the productivity of employee, increase the public services, adaptable in current condition of pandemic covid-19 cases in Indonesia.